QUANTITATION OF A NOVEL ENGINEERED ANTI-INFECTIVE HOST DEFENSE PEPTIDE, ARV-1502: PHARMACOKINETIC STUDY OF DIFFERENT DOSES IN RATS AND DOGS

Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs

The designer proline-rich antimicrobial peptide (PrAMP) Chex1-Arg20 amide (ARV-1502) is active against Gram-negative and Gram-positive pathogens in different murine infection models when administered parenterally and possesses a wide therapeutic index.Here we studied the pharmacokinetics of ARV-1502 for the first time when administered intramuscula

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Boosting precision crop protection towards agriculture 5.0 via machine learning and emerging technologies: A contextual review

Crop protection is a key activity for the sustainability and feasibility of agriculture in a current context of climate change, which is causing the destabilization of agricultural practices and an increase in the incidence of current or invasive pests, and a growing world population that requires guaranteeing the food supply chain and ensuring foo

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Application of the Hess-Brezowsky classification to the identification of weather patterns causing heavy winter rainfall in Brittany (France)

An accurate knowledge of the weather patterns causing winter rainfall over the Scorff watershed in western Brittany (W.France) was developed prior to studies of the impact of the climate factor on land use nacrack.com management, and of the hydrological reponses to rain-producing weather patterns.These two studies are carried out in the context of

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